Extracellular Matrix and the Liver Approach to Gene Therapy

Extracellular Matrix and the Liver is an overview of recent progress in understanding the cellular and molecular basis of liver fibrosis, with a review of prospective targets for therapy. Cirrhosis of the liver has been believed to be progressive and incurable. However, interferon therapy for HCV-positive chronic hepatitis and/or liver cirrhosis shows dramatic recovery in some cases. This volume addresses the new strategies for the treatment of all kinds of liver cirrhosis. The chapters are divided into five sections: * Basic Science of Extracellular Matrix * Cells Responsible for Extracellular Matrix Production * Activation Mechanism of Hepatic Stellate Cells and Signal Transduction * Basic Science for Extracellular Matrix Metabolism Including Enzymes and Their Inhibitors * Matrix Metalloproteinases and Tissue Inhibitors for Matrix Metalloproteinases * New Strategies for the Treatment of Liver CirrhosisOkazaki, Isao is the author of 'Extracellular Matrix and the Liver Approach to Gene Therapy' with ISBN 9780125252515 and ISBN 012525251X.