Understanding DNA The Molecule & How It Works

We see DNA structures so often that it is frequently taken for granted that the molecule should not be anything but an aesthetically spiraling helix. But why should it assume such a nice structure? The functional properties of any molecule are directly related to, and affected by, its structure. This is especially true for DNA, the molecular that carries the code for all life on earth. The third edition of Understanding DNA has been entirely revised and updated, and expanded to cover new advances in our understanding. It explains, step by step, how DNA forms specific structures, the nature of these structures and how they fundamentally affect the biological processes of transcription and replication. * describes the basic units of DNA and how these form the double helix * characterizes the various types of DNA double helix that have been found * explains how and why DNA twists and curves * discusses the mechanisms of DNA supercoiling * summarizes the assembly of DNA and protein into chromosomes * describes the latest work on protein-DNA complexes * outlines the methods used to study DNA structure * summarizes recent studies of DNA in disease and medicine * explains mechanisms of non-classical inheritance * contains over 130 illustrations, some in full colour * contains simple exercises and further reading at the end of chapters Written in a clear, concise and lively fashion, Understanding DNA is essential reading for all molecular biology, biochemistry and genetics students, to newcomers to the field from other areas such as chemistry or physics, and even for seasoned researchers, who really want to understand DNA. From reviews of the first edition Stylish beautifully crafted, with a logical step-by-step approach to the subject. A book from which the advanced undergraduate will benefit, and which will also generate a refreshing perspective for experts - NATURE Authorative and lucid - SIR AARON KLUGCalladine, Chris R. is the author of 'Understanding DNA The Molecule & How It Works', published 2004 under ISBN 9780121550899 and ISBN 0121550893.